Journal of the European Society for Gynaecological Endoscopy


Oxidised cellulose-based reaction mimicking a suspicious ovarian mass: a case report and a systematic review

R. Nasir1, I. Alkiumi1, E. Alzahmi1, B. AlMaamari1, H. Gharbi1, Z. Hakim1, P. Koninckx2, A. Wattiez1

1 Obstetrics and gynaecology department, Latifa Women and Children Hospital, Dubai, UAE
2 Prof emeritus Obstetrics and Gynecology KULeuven, Leuven, Belgium, the University of Oxford, Oxford, UK, University Cattolica, Rome, Italy


Hemostatic agent, Surgicel reaction, suspicious ovarian mass, regenerated oxidised cellulose, Surgicel

Published online: Jun 28 2024


Oxidised regenerated cellulose was introduced 60 years ago to control diffuse bleeding from large surfaces. Although considered safe and effective, foreign body reactions can mimic suspicious masses in several organs. We describe the third case, reported in PubMed, of an oxidised regenerated cellulose-based granuloma mimicking a suspicious ovarian tumour on MRI. During surgery, the diagnosis was suspected by granulomatous tissue and confirmed by pathology. The follow-up after the excision was uneventful. Although a rare complication, physicians should be aware of this presentation and of the recommendation to remove excess Surgicel after the bleeding has stopped.